The recently rediscovered ToonMakers' Sailor Moon was an attempt to cash in on the then highly popularly power rangers franchise using both original live action footage and animation. You could argue if it was doomed from the start, but let's say it does decently well,runs for like three seasons, what effect would it have the entertainment industry ? Would the success lead to more female led shows ? More importantly would it 'kill' anime's chances in America ?! Probably not. There will be more American remakes but some bastard eventually is going to realize it's cheaper to just dub than make a whole ass show; when Pokemon comes stateside (I doubt they'd go the remake route) most studios would realize this. I'd wager that during the 2000s and early 2010s the show is a target of mockery similar to 4Kids and Robotech, as the years go by creators influenced by it and a general change in zeitgeist would turn opinion more fond. So the biggest impact is the lessening of exposure of anime to that generation of creators. Also Code Lyoko probably would have been gotten a remake where the CGI scenes are dubbed while the traditionally animated parts are live action.